LUPUS DISEASE

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LUPUS DISEASE

Lupus is a long-term autoimmune disease in which the body’s immune response or bone marrow becomes hyperactive and attacks normal, healthy tissue. Symptoms include inflammation, swelling, and damage to the joints, skin, kidneys, blood, heart, and lungs.

In other words, it’s the system that differentiates self from non-self and protects the body from foreign substances and pathogenic organisms by producing an immune response. It includes organs such as the thymus, the spleen and the nodes and also the tissues such as the bone marrow and the cell such as lymphocytes including the B cells and the T cells.

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TYPES OF LUPUS DISEASE

There are different kinds of lupus. This article will focus mainly on systemic lupus erythematosus (SLE) because it’s one of the fast-rising and also common among us these recent days, but other types comprehend discoid, drug-induced, and neonatal lupus.

Systemic lupus erythematosus

SLE is the most familiar type of lupus. It is a systemic condition. This means it has an impact on the body. The symptoms can range from mild to severe.

It is more severe than other types of lupus, such as discoid lupus, because it can affect any of the body’s organs or organ systems. It can cause kindling’ or setting on fire in the skin, joints, lungs, kidneys, blood, heart, or a combination of these.

Causes

Lupus is an autoimmune condition, but the exact cause is unclear.

What goes wrong?

The immune system protects the body and fights off antigens, such as viruses, bacteria, and germs.

As a result, the immune system directs antibodies against both the healthy tissue and the antigens. This causes swelling, pain, and tissue damage.

The most common type of autoantibody that develops in people with lupus is an antinuclear antibody (ANA).

Risk factors: Hormones and Genes

Lupus can develop in response to a number of factors. These may be hormonal and genetics or a combination of these.

1) Hormones

Hormones are chemical substances that control and regulate the activity of certain cells or organs.

Hormonal activity will explain more about the following risk factors:

Sex: The U.S. National Institutes of Health note that females are 9 times more likely to have lupus than males.

Age: Symptoms and diagnosis often occur between the ages of 15 and 45 years, during the childbearing years. However, 20% of cases appear after the age of 50 years, according to Genetics Home References.

2) Genetic factors

Researchers have not proved that any specific genetic factor causes lupus, although it is more common in some families.

Genetic factors may be the reason why the following are risk factors for lupus:

Race: People of any background can develop lupus, but it is two to three times more common in people of colour, compared with the white population. It is also more common in Hispanic, Asian, and Native American women.

Family history: A person who has a first- or second-degree relative with lupus will have a higher risk of developing it.

Are children at risk?:Get rid of lupus

Lupus is rare in children under the age of 15 years unless their birth mother has it. In this case, a child may have lupus-related heart, liver, or skin problems.

Symptoms: Get rid of lupus

Lupus has a wide range of symptoms, including:

• Swelling in the legs or around the eyes
• Swollen glands, or lymph nodes
• Skin rashes, due to bleeding under the skin
• Mouth ulcers
• Sensitivity to the sun
• Chest pain upon deep breathing

Other complications: Get rid of lupus

Having lupus increases the risk of a number of health problems:

Infection: Infection becomes more likely because both lupus and its treatments weaken the immune system. Common infections include urinary area infections, respiratory infections, yeast infections, salmonella, herpes, and herpes zoster.

Pregnancy complications: Women with lupus have a higher risk of pregnancy loss, preterm birth, and preeclampsia, a condition that includes high blood pressure. To reduce the risk of these complications, doctors often recommend delaying pregnancy until lupus has been under control for at least 6 months.

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